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08 NOVEMBER 2012

Dara Ó Briain's Science Club: The Story of Inheritance

"This first episode in a new six–part science series presented by Dara Ó Briain takes a look at the weird and wonderful world of reproduction and inheritance.

Dara chats to leading biologist Professor Steve Jones and finds out how the bicycle did more to improve the human immune system than any other invention, comedian Ed Byrne discovers just how closely related he is to a Neanderthal and materials scientist and engineer Mark Miodownik creates a DNA cocktail with the help of some strong Polish vodka.

Dara is also joined by neuroscientist Tali Sharot, who explores the cutting–edge science of epigenetics and reveals how exercise can change your DNA. Science journalist Alok Jha asks if the human genome project was oversold and the studio audience are put to the test in the elusive search for attraction.

Combining lively and in–depth studio discussion with exploratory films and on–the–spot reports, Dara Ó Briain's Science Club takes a single subject each week and examines it from lots of different and unexpected angles, from sex to extinction, Einstein to space exploration and brain chemistry to music. It brings some of the world's foremost thinkers together to share their ideas on everything, from how to avoid asteroid impact to whether or not we are still evolving."

(BBC Two, UK)

Fig.1 this animation is from Episode 1 or 6 of Dara Ó Briain's Science Club, Tuesday 6 November at 9pm on BBC Two, animated by 12Foot6, Published on YouTube on 5 Nov 2012 by BBC.

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12Foot619532D2D animationAlok Jhaanimated information graphicsanimation • Antonie van Leeuwenhoek • AristotleBBC TwobloodcellchromosomeDara O BriainDNA • double helix • Ed Byrne • egg • epigenetics • female testicles • fly • Francis Crick • Francis Galton • genes • Gregor Mendel • history of ideashuman genome projectillustration to visually communicate informationinheritance • James Watson • Mark Miodownik • materials scientist • miniature • Niels Stensen • ovaries • ovary • peas • preformationism • reproduction • Robert Bakewell • scienceScience Club (tv) • science series • sequential artsexsperm • Steve Jones • story of sciencestudio audience • studio discussion • Tali Sharottree of lifevisual representations of scientific concepts

CONTRIBUTOR

Simon Perkins
04 JULY 2009

Mitochondrial DNA sequences in ancient Australians: Implications for modern human origins

"Lake Mungo 3 is the oldest (Pleistocene) 'anatomically modern' human from whom DNA has been recovered. His mtDNA belonged to a lineage that only survives as a segment inserted into chromosome 11 of the nuclear genome, which is now widespread among human populations. This lineage probably diverged before the most recent common ancestor of contemporary human mitochondrial genomes. This timing of divergence implies that the deepest known mtDNA lineage from an anatomically modern human occurred in Australia; analysis restricted to living humans places the deepest branches in East Africa. The other ancient Australian individuals we examined have mtDNA sequences descended from the most recent common ancestor of living humans. Our results indicate that anatomically modern humans were present in Australia before the complete fixation of the mtDNA lineage now found in all living people. Sequences from additional ancient humans may further challenge current concepts of modern human origins."

(Gregory Adcock, Elizabeth Dennis, Simon Easteal, Gavin Huttley, Lars Jermiin, William Peacock and Alan Thorne)

Adcock, G. J., E. S. Dennis, et al. (2001). "Mitochondrial DNA sequences in ancient Australians: Implications for modern human origins." Archaeology in Oceania 36(3): 163-163.

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19742001Aboriginal AustraliansAfrica • Alan Thorne • alternative explanation • anatomically modern human • ancient DNA • ancient humans • ancient peoplearchaeology • Archaeology in Oceania • AsiaAustraliaAustralian National University • bone fragments • burial ritual • cell biologychromosome • common ancestor • cremated remains • divergence • divergent selection • divergent variation • DNAEast Africa • Elizabeth Dennis • emergence of modern humans • Europe • evolutionary lineage • evolutionary process • evolutionary theoryevolutionary tree • female skeleton • fixation • fossil evidence • fossil specimen • Gavin Huttley • genetic lineage • genetic pool • genetic relationship • genetic sequence • genome • genotyping analysis • Gregory Adcock • Homo erectus • Homo sapiens • human evolutionhuman history • human populations • human speciesIndiaIndigenous Australians • Lake Mungo • Lars Jermiin • living humans • Mamanwa people • mitochondria • mitochondrial genome • modern human origins • mtDNA lineage • multiregional evolution • multiregional explanation • multiregional origin of modern humans hypothesis • Mungo Lady • Mungo Man • New South Walesochre • origin of modern humans • out-of-Africa hypothesis • Papua New GuineaPeoples Republic of China • pleistocene • Proceedings of the National Academy of Sciences (PNAS) • Simon Easteal • simultaneous development • skeletal remains • skeletonSouth East Asianspeciation • subspecies • William Peacock

CONTRIBUTOR

Simon Perkins
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